Stephen K Tyring Selected Research

Canavan Disease (Leukodystrophy, Spongiform)

1/2006	Canavan disease: studies on the knockout mouse.
7/2005	Aspartoacylase gene knockout in the mouse: impact on reproduction.
8/2004	Aspartoacylase deficiency does not affect N-acetylaspartylglutamate level or glutamate carboxypeptidase II activity in the knockout mouse brain.
9/2003	Canavan disease: a monogenic trait with complex genomic interaction.
9/2003	Metabolic changes in the knockout mouse for Canavan's disease: implications for patients with Canavan's disease.
8/2003	Expression of glutamate transporter, GABRA6, serine proteinase inhibitor 2 and low levels of glutamate and GABA in the brain of knock-out mouse for Canavan disease.
5/2003	Adeno-associated virus-mediated aspartoacylase gene transfer to the brain of knockout mouse for canavan disease.

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Stephen K Tyring Research Topics

Disease

32	Neoplasms (Cancer) 06/2021 - 05/2002
29	Infections 09/2018 - 03/2002
28	Herpes Zoster 05/2020 - 09/2003
21	Psoriasis (Pustulosis Palmaris et Plantaris) 10/2022 - 11/2003
16	Virus Diseases (Viral Diseases) 05/2015 - 10/2002
12	Warts (Wart) 10/2020 - 04/2002
11	Papillomavirus Infections 01/2021 - 04/2002
10	Acne Vulgaris 05/2022 - 03/2002
10	Squamous Cell Carcinoma (Epidermoid Carcinoma) 04/2022 - 09/2002
10	Pain (Aches) 01/2017 - 09/2003
9	Carcinogenesis 04/2020 - 05/2002
9	Postherpetic Neuralgia 10/2013 - 06/2006
9	Herpes Genitalis (Genital Herpes) 10/2008 - 01/2003
8	Exanthema (Rash) 01/2014 - 04/2002
8	Communicable Diseases (Infectious Diseases) 03/2009 - 04/2003
7	Phenylketonurias (Phenylketonuria) 01/2007 - 12/2003
7	Canavan Disease (Leukodystrophy, Spongiform) 01/2006 - 05/2003
6	Melanoma (Melanoma, Malignant) 01/2021 - 03/2013
6	Skin Neoplasms (Skin Cancer) 01/2020 - 10/2003
6	Acquired Immunodeficiency Syndrome (AIDS) 01/2019 - 04/2002
6	Uterine Cervical Neoplasms (Cancer of the Cervix) 04/2015 - 01/2003
6	Actinic Keratosis 06/2014 - 09/2004
6	Chickenpox 01/2014 - 04/2003
5	Skin Diseases (Skin Disease) 01/2022 - 09/2004
5	Herpes Simplex 01/2014 - 10/2002
4	Merkel Cell Carcinoma 07/2022 - 04/2012
4	Atopic Dermatitis (Atopic Eczema) 01/2022 - 08/2010
4	Psoriatic Arthritis 01/2022 - 01/2018
4	Basal Cell Carcinoma (Rodent Ulcer) 01/2021 - 09/2004
4	Disease Progression 01/2020 - 11/2003
4	Carcinoma (Carcinomatosis) 07/2018 - 08/2002
4	Epidermodysplasia Verruciformis 03/2013 - 10/2003
3	Rosacea (Acne Rosacea) 05/2022 - 01/2012
3	Rheumatoid Arthritis 01/2022 - 11/2011
3	Inflammation (Inflammations) 01/2020 - 01/2018
3	Sexually Transmitted Diseases (Sexually Transmitted Disease) 10/2019 - 05/2005
3	HIV Infections (HIV Infection) 01/2019 - 08/2002
3	Neuralgia (Stump Neuralgia) 01/2017 - 06/2003
3	Condylomata Acuminata (Genital Wart) 04/2015 - 04/2002
3	Herpes Labialis (Fever Blister) 06/2006 - 10/2002
3	Mycoses (Diseases, Fungus) 12/2005 - 01/2004
3	Hepatitis B 04/2004 - 04/2003
3	Uterine Cervical Dysplasia 09/2002 - 08/2002
2	Soft Tissue Infections 01/2022 - 01/2022
2	Kaposi Sarcoma (Kaposi's Sarcoma) 01/2021 - 09/2003
2	Cicatrix (Scar) 01/2021 - 05/2017

Drug/Important Bio-Agent (IBA)

26	VaccinesIBA 01/2020 - 04/2002
21	Antiviral Agents (Antivirals)IBA 01/2017 - 04/2002
18	DNA (Deoxyribonucleic Acid)IBA 01/2021 - 06/2002
11	CytokinesIBA 05/2020 - 05/2002
10	Anti-Bacterial Agents (Antibiotics)IBA 02/2022 - 03/2002
10	Valacyclovir (Valtrex)FDA LinkGeneric 01/2017 - 10/2002
8	AntigensIBA 07/2022 - 06/2002
8	Imiquimod (Aldara)FDA LinkGeneric 01/2015 - 10/2002
7	Pharmaceutical PreparationsIBA 01/2021 - 09/2004
7	Famciclovir (Famvir)FDA LinkGeneric 04/2009 - 09/2003
7	Acyclovir (Aciclovir)FDA LinkGeneric 09/2007 - 04/2002
6	Herpes Zoster VaccineIBA 10/2013 - 02/2007
6	EnzymesIBA 09/2012 - 09/2003
6	aspartoacylaseIBA 07/2006 - 05/2003
5	Biomarkers (Surrogate Marker)IBA 01/2020 - 01/2018
5	Adalimumab (Humira)FDA Link 10/2019 - 01/2008
5	sialosyl-T antigenIBA 04/2019 - 03/2016
5	3-ingenyl angelateIBA 06/2014 - 03/2012
4	Tretinoin (Retinoic Acid)FDA LinkGeneric 12/2020 - 09/2002
4	Papillomavirus Vaccines (HPV Vaccines)IBA 01/2020 - 01/2010
4	Interleukin-6 (Interleukin 6)IBA 01/2018 - 06/2002
4	Etanercept (Enbrel)FDA Link 08/2017 - 03/2008
4	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 03/2013 - 06/2003
4	Amino Acids FDA Link 01/2007 - 08/2004
4	N-acetylaspartate (N-acetyl aspartate)IBA 01/2006 - 09/2003
4	Interleukin-10 (Interleukin 10)IBA 01/2004 - 08/2002
3	sarecyclineIBA 05/2022 - 09/2018
3	Tetracycline (Achromycin)FDA LinkGeneric 05/2022 - 09/2018
3	Doxycycline (Periostat)FDA LinkGeneric 02/2022 - 07/2015
3	tofacitinibIBA 01/2022 - 05/2015
3	Ustekinumab (CNTO 1275)FDA Link 04/2021 - 05/2008
3	Adrenal Cortex Hormones (Corticosteroids)IBA 11/2020 - 12/2007
3	Tumor Viral Antigens (Large T Antigen)IBA 04/2020 - 11/2014
3	Immunoglobulin G (IgG)IBA 01/2020 - 01/2017
3	Ointments (Pastes)IBA 01/2019 - 01/2012
3	Glycoproteins (Glycoprotein)IBA 01/2018 - 05/2005
3	Proteins (Proteins, Gene)FDA Link 01/2016 - 07/2004
3	Cidofovir (Vistide)FDA Link 01/2015 - 04/2002
3	RetinoidsIBA 01/2015 - 09/2002
3	Gabapentin (Neurontin)FDA LinkGeneric 01/2014 - 12/2007
3	InterferonsIBA 08/2010 - 09/2003
3	Phenylalanine (L-Phenylalanine)FDA Link 01/2007 - 12/2003
3	resiquimodIBA 11/2004 - 04/2002
3	NucleosidesIBA 11/2004 - 09/2003
2	selinexorIBA 07/2022 - 01/2022
2	Janus Kinase InhibitorsIBA 01/2022 - 05/2015
2	ParaffinIBA 06/2021 - 03/2013
2	Biological ProductsIBA 01/2021 - 03/2006
2	Interleukin-23 (Interleukin 23)IBA 01/2021 - 01/2017

Therapy/Procedure

47	Therapeutics 07/2022 - 04/2002
4	Highly Active Antiretroviral Therapy (HAART) 01/2019 - 05/2002
2	Drug Therapy (Chemotherapy) 07/2022 - 01/2018
2	Biological Therapy 04/2021 - 04/2012
2	Aftercare (After-Treatment) 11/2020 - 10/2013